October 5-9, 2025, Saint-Malo, France
DYRK1A, related kinases and human diseases conference
General presentation
Dyrk1A related kinases and human diseases conference will focus on DYRK1A and related kinases, including structural, regulatory and functional aspects, substrates and interactors, functions at cell and organism levels as well as development and potential therapeutic use of selective pharmacological inhibitors in various indications.
About the event
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DYRKs (‘dual specificity, tyrosine phosphorylation regulated kinases’) (DYRK1A, 1B, 2, 3, 4) play key roles in mRNA splicing, chromatin transcription, DNA damage repair, aging, cell survival, cell cycle, differentiation, endocytosis, neuronal development and functions, synaptic plasticity, mytochondrial functions. Inhibition of DYRKs may find applications in Down syndrome, Alzheimer’s disease and tauopathies, Parkinson’s disease, diabetes, myocardial infarction, otitis, osteoarthritis, viral infections, various cancers, etc. The closely related CLKs (‘cdc2-like kinases’) (CLK1, 2, 3, 4) also play essential functions in Alzheimer’s disease and tauopathies, alternative splicing, various viral infections, cancers, etc. DYRK and CLK orthologs are found in plants, fungi, yeast and unicellular parasites.
Abstract submission
Deadline: July 31, 2025
DOWNLOAD THE TEMPLATE, don’t try to fill it online :
DYRK1A Conference Abstract – Surname
You can download the PDF form by selecting “…” on the top right.
FILL IT, save a copy and SEND :
When ready, send your PDF abstract with your surname in the title to :
dyrk-conference@perha-pharma.com
Layout instructions :
Title and authors:
- 1 page maximum written in English
- Arial 11
- Title in Bold
- Underline presenting author
- Add your contact information: e-mail, address
Abstract:
- Line Spacing 1
- maximum 2500 to 3000 characters (with spaces)
- References: maximum 800 characters (with spaces): 1 to 3 compact references
- Funding: maximum 350 characters (with spaces)
When ready send your abstract to our e-mail address: dyrk-conference@perha-pharma.com
Invited Speakers
Contact: dyrk-conference@perha-pharma.com
Walter BECKER, Aachen, Germany
DYRK1B, a cancer drug target
Marco CALZADO CANALE, Cordoba, Spain
DYRK2 as a novel modulator of cancer pathways
John CRISPINO, Memphis, USA
Amplification of DYRK1A drives transformation to acute leukemia
Mara DIERSSEN, Barcelona, Spain
Role of DYRK1A in glucose homeostasis and food intake
Cristina FILLAT, Barcelona, Spain
Role of DYRK1A in pancreatic cancer tumor microenvironment
Maria GAITANOU, Athens, Greece
DYRK1B in motor neuron development in health and disease
Yann HERAULT, Strasbourg, France
Lessons learnt from studying DYRK1A in mammalian models for MRD7 and Down syndrome
Christopher HULME, Tucson, USA
The development of an ultra-selective DYRK1A PROTAC, DYR684
Mattias LAUTH, Marburg, Germany
DYRK1B in pancreatic cancer
Mattias LINDBERG, Roscoff, France
Affinity chromatography purification of DYRK1A and associated proteins
Larisa LITOVCHICK, Richmond, USA
Understanding the multifunctional DYRK1A kinase through characterization of its interacting proteins
Arya MANI, Yale New Haven, USA
DYRK1B regulates beta cell function and structure by orchestrating microtubule assembly and ciliary structure
Laurent MEIJER, Roscoff, France
Phase 1 clinical evaluation of the DYRK1A inhibitor Leucettinib-21
Jamileh MOVASSAT, Paris, France
DYRK1A inhibitors for beta cell proliferation to treat diabetes
Dean NIZETIC, London, U.K
Dose imbalance of DYRK1A is a causative factor for the developmental progeria in Down syndrome
Amélie PITON, Illkirch, France
Characterization of DYRK1A syndrome, a frequent form of neurodevelopmental disorder
Victor TYBULEWICZ, London, U.K.
Increased dosage of DYRK1A is required for congenital heart defects and many other pathological phenotypes in Down syndrome
Nora VÖGTLE, University of Heidelberg, Germany
News from the DYRK1A – mitochondria axis
Matthew WOLF, Charlottesville, USA
The inhibition of DYRK1A improves cardiac function after myocardial infarction
Instructions for speakers
There will be no poster sessions. We will try to have as many people as possible, especially students and post-docs, presenting their results. Besides invited speakers, submitted abstracts will be selected for long (15 min) or short (5 min) oral presentations (+ 5 min discussion).
Registration
KEY DATES
Abstracts deadline : July, 31st, 2025
Early bird registration deadline : April 30th, 2025
Latest registration deadline : August 31st, 2025
Onsite registration : October 5th, 2025 at 3:00 pm
Plenary Session : October 5th, 2025 at 6:30 pm
Start of the conference : October 6th, 2025 at 9:00 pm
End of the conference : October 9th, 2025 at 12:00 pm
Excursion to the Mont-Saint-Michel : October 9th, 2025 from 1:30 pm to 7:00 pm (upon registration)
Registration costs & payment information
Please download the registration form :
Registration form Dyrks conference 2025
Don’t try to fill it online. You can download the PDF form by selecting “…” on the top right.
Fill it and send it back by mail. There is no online payment.
dyrk-conference@perha-pharma.com
Registration includes access to all conferences, program, welcome cocktail, coffee/tea breaks and lunches.
Early bird registration costs
PhD Students* : 450 €
Academic and Start-up : 750 €
Industry : 900 €
Late registration costs
PhD Students* : 550 €
Academic and Start-up : 850 €
Industry : 1200 €
* Photocopy of student card required
Optional excursion : 60 € /pers.
Excursion is subject to prior registration and payment (during your on-line registration). More information will be available soon.
Program and book of abstracts
The final program will be available in September 2025.
October 5th, 2025 at 3:00 pm : Opening of registrations and welcome cocktail at Le Palais du Grand Large, Saint-Malo
A book of abstracts will be offered to the participants at registration
October 6th, 7th and 8th, 9:00 am to 7:00 pm : schedule of the sessions to be determined
October 9th, 9:00 am to 12:00 pm : schedule of the sessions to be determined
October 9th, 1:30 pm to 7:00 pm : Excursion to the Mont-Saint-Michel and its Abbey
Excursion to the Mont-Saint-Michel and its Abbey
In the afternoon of October 9th we organize an excursion to the Mont-Saint-Michel and its Abbey. Excursion is subject to prior registration and payment (during your on-line registration).
Cost is 60 € per person.
If you are interested in participating, tick the box in the abstract template or simply send us an e-mail before June 6th, 2025.
Visit schedule :
1:30 pm : Departure in bus from Saint-Malo
2:30 pm : Guided visit of the Mount and Abbey
5:45 pm : Return to the bus
6:00 pm : Bus departure
7:00 pm : Arrival in Saint-Malo
Previous DYRK1A conferences
Visit our company website : Perha Pharmaceuticals conferences
to read the books of abstracts of 2017 and 2022
DYRK1A related kinases and human diseases conferences
Have A Look At The
Event Schedule
Venue
Conference Centre
Palais du Grand Large
Centre des congrès, Saint-Malo
1 Quai Duguay-Trouin
35 400 Saint-Malo
https://www.pgl-congres.com/
- TGV in 2h15 from Paris
- The TGV train station is 5min away by bus 20min on foot
- Rennes airport at 50 min
- 1160 parking places around the Palais
- 1 hour from Rennes by car, 2 hours from Nantes and 4 hours from Paris
Accomodation
Le Palais du Grand Large in Saint Malo proposes a list of Hotels.
Saint-Malo & Brittany
Tourism office : www.saint-malo-tourisme.com
St Malo city hall : www.ville-saint-malo.fr
Thank you for your participation to the DYRK1A conference in 2022
Sponsors
